New PSP for Lorlatinib in 2nd line ALK translocated - Amivantamab + Lazertinib in first line mEGFR - Amivantamab + CT in second line EGFR post Osimertinib -

Update 5 October 2025

Crizotinib

Lung – NSCLC / Metastatic

Québec / Canada

4 mos.

positive 4 September 2012

Clinical Trials

3 yrs

positive 25 April 2012

Health Canada

7 days.

positive 1 October 2015

INESSS (QC)

positive 21 July 2015

pCODR (CA)

3 mos.

positive 8 October 2015

pCPA

positive 1 February 2016

RAMQ / LM

Comparison with other countries

United States

United States

7 mos.

positive 26 August 2011

FDA approval

Canada

Canada

5 mos.

positive 25 April 2012

Health Canada

Europe

Europe

positive 23 October 2012

EMA approval

RAMQ Insurance

For patients covered by the Quebec’s Health Insurance Plan / RAMQ, please fill out the form directly on the RAMQ website and submit it for approval.

Private Insurance

For patients with a personal health insurance, search for the drug (using sometimes its commercial name) download and fill out the appropriate prior authorization form. If you are unable to find the drug, you should fill out the General Form available on the same page (contact me if you have trouble locating it).
Manulife and Sunlife have a more complicated way, links will download a detailed pdf, please open it and follow the instructions :

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