New PSP for Lorlatinib in 2nd line ALK translocated - Amivantamab + Lazertinib in first line mEGFR - Amivantamab + CT in second line EGFR post Osimertinib -

Update 5 October 2025

Gemcitabine + Cis/Carbo

Bladder / Metastatic

While many advocate for the use of Cisplatin in the metastatic setting due to the higher response rate and better long term data, we all know how difficult is to adminsiter Cisplatin in this population with fragile renal function.

The use of chemotherapy now comes post EV-Pembro or for the ones not eligible for this regimen or when it is not accessible or available.

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Gemcitabine + Cis/Carbo

Bladder / Metastatic

Québec / Canada

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