Mise à jour 5 octobre 2025

Carboplatin + Etoposide (CRT)

Lung – SCLC / Limited Stage

Québec / Canada

HeCOG

Four cycles of systemic therapy with Carboplatin can be an alternative for LS-SCLC when cisplatin is contraindicated or not tolerated.

Since the use of GCSF is not recommended / permitted during CRT, this combination can be very neutropenic

(I believe it has a high probability to complicate the whole treatment if given at AUC 6 and E 100, I usually give Carbo AUC 4-5 and E 80-100mg/m2 days 1-3)

Sequential CRT can also be another option for the less fit population, but it is a less efficient strategy.

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Carboplatin + Etoposide (CRT)

Lung – SCLC / Limited Stage

Québec / Canada

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